Some of the listed biographies contain a great amount of information on the subject, others however may only be a paragraph or a few lines. Most of the information has been taken from the books we provide free online.
- Samuel, Clarence L. Mrs.
- Samuel, P. W. Mrs.
- Samuel, William R. Mrs.
- Sanders, Benjamin F. Mrs.
- Sanders, Bryan E. Mrs.
- Sanders, Madison,
- Sanders, W. E.
- Sandifer, Bert E.
- Santos
- Sassacus
- Sequoya
- Sassaba
- Satanta
- Scarface Charlie
- Scarouady
- Schonchin
- Scott, James A.
- Scott, John S.
- Seattle
- Seaver, W. F.
- Secondyne, Simon
- Selocta, A Creek Chief
- Sepulpa, William A.
- Sequoyah or George Guess, Inventor of the Cherokee alphabet
- Setangya
- Severs, Frederick B.
- Sevier, William Penn
- Shabonee
- Shackelford, James M., Judge
- Shade, Henry
- Shahaka
- Shahaka, A Mandan Chief
- Shakopee
- Sharitarish, Pawnee Chief
- Shauhaunapotinia, An Ioway Chief
- Shavehead
- Shepard, Harrison O.
- Shingaba W’Ossin, A Chippeway Chief
- Shingabawassin
- Simpson, John F.
- Sisson, Pearl V. Mrs.
- Sitting Bull, Sioux Indian Chief
- Sitting Bull, The Great Dakota Leader
- Skinner, Ray N. Mrs.
- Skinner, Nathaniel
- Sleeper, Minnie Mrs.
- Sleeping Wolf
- Sloan, James E.
- Small, James, M.D
- Smallwood, B. F.
- Smith, A. J. Mrs.
- Smith, Charles Scott
- Smith, Ford Mrs.
- Smith, Fred
- Smith, George W.
- Smith, Jasper E. Mrs.
- Smith, John A.
- Smith, John M.
- Smith, Red Bird
- Smith, Richard Lafayette Mrs.
- Smith, Richard M.
- Smith, Wiley
- Smohalla
- Snider, Elbert Jacob
- Snodgrass T. L. Mrs.
- Sparlin, Benjamin F.
- Spotted Tail
- Springston, John L.
- Squando
- Squanto
- Standiford, J. F.
- Starr, Bluford W.
- Starr, Caleb W.
- Starr, Ellis
- Starr, John Caleb
- Starr, Walter A. Judge
- Stewart, James O.
- Stidham, George W. Jr.
- Stidham, George Washington Hon.
- Stiles, Charles W.
- Strange, Cicero, J.
- Strange, William J.
- Stumanu, A Flathead Boy
- Sullivan, Frank R.
- Sunday, Andrew
- Swain, Mrs. Rebecca M.