The following were Cherokee settlements:
- Aguaquiri (?)
- Amahyaski
- Arnakalali
- Amohi
- Anisgayayi
- Anuyi
- Aguohee
- Aracuchi
- Atsiniyi
- Aumuchee
- Ayaliliyi
- Big-Island
- Briertown
- Broomtown
- Brown’s Village
- Buffalo Fish
- Canuga
- Catatoga
- Chagee
- Chattanooga
- Chatuga
- Cheesoheha
- Chewase
- Chicherohe
- Chickamauga
- Chilhowee
- Couisca
- Conontoroy
- Conoross
- Coowheescoowee (district)
- Cotocanahut
- Cowee
- Coweeshee
- Coyatee
- Crayfish Town
- Creek Path
- Crowmocker
- Crow Town
- Cuclon
- Cusawatee
- Dulastunyi
- Dustayalunyi
- Echota
- Ecochee
- Elakulsi
- Ellijay
- Estatoee
- Etowah
- Euforsee
- Fightingtown
- Frogtown
- Guasuli
- Gulaniyi
- Gusti
- Gwalgahi
- Half way Town
- Hemptown
- Hickory Log
- High Tower Forks
- Hiwassee
- Ikatikunahita
- Itseyi
- Ivy Log
- Johnstown
- Jore
- Kalanunyi
- Kanastunyi
- Kansaki
- Kanutaluhi
- Kawanuyi
- Keowee
- Kituhwa
- Kuhlahi
- Kulahiyi
- Kulsetsiyi
- Leatherwood
- Long IsÂland
- Lookout Mountain
- Naguchee
- Nanatlugunyi
- Nantahala
- Natuhli
- Nayuhi
- Nickajack
- Niowe
- Noewe
- Nowe
- Nucassee
- Nununyi
- Ocoee
- Oconaluftee
- Oconee
- Olagatano
- Ooltewah
- Oothcaloga
- Paint Town
- Pine Log
- Quacoshatchee
- Qualatchee
- Qualla
- Quanusee
- Quinahaqui
- Rabbit Trap
- Red Bank
- Red Clay
- Running Water
A former Cherokee town on the south east bank of Tennessee River, below Chattanooga, near the northwest. Georgia line, and 4 m. above Nickajack. It was settled in 1782 by Cherokee who espoused the British cause in the Revolutionary war, and was known as one of the Chickamauga towns. It was destroyed in the fall of 1794. See Royce in 5th Rep. B. A. E., map, 1887; Mooney in 19th Rep. B. A. E., 54, 78, 1900. - Saguahi
- Sanderstown
A former Cherokee settlement in N. E. Alabama, probably taking its name from some prominent mixed-blood. - Selikwayi (Selikwâ‛yĭ)
A Cherokee settlement, about the time of the removal of the tribe to the west in 1839, on Sallacoa Creek, probably at or near the present Sallacoa, Cherokee County, Georgia. The name is that of a small green snake, and of a tall broad-bladed grass bearing a fancied resemblance to it.- Sallicoah – Doc. of 1799 quoted by Royce in 5th Rep. B. A. E., 144, 1887.
- Seneca (Iʽsû‛nigû)
A former important Cherokee settlement on Keowee River, about the mouth of Conneross Creek, in Oconee, County, South Carolina. Hopwell, the county seat of General Pickens, where the famous treaty was made in 1785, was near it, on the east side of the river. Mooney in 19th Rep. B.A.E., 522, 1900.- Sennikaw – Royce in 5th Rep. B.A.E., map, 1887.
- Sinica – Bartram Travels, 372, 1792.
- Setsi (Sĕ‛tsĭ)
A traditional Cherokee settlement on the south side of Valley River, about 3 miles below Valleytown, in Cherokee County, North Carolina. There is a mound at this place. Mooney in 19th Rep. B.A.E., 531, 1900. - Sitiku
A former Cherokee settlement on Little Tennessee River at the entrance of Citico Creek, in Monroe County, Tennessee. The name, which can not be translated, is commonly spelled Citico, but appears also as Sattiquo, Settico, Settacoo, Sette, Sittiquo, etc. Mooney in 19th Rep. B.A.E., 531, 1900.- Settacoo – Timberlake, Memoirs, map 1765.
- Sette – Bartram, Travels, 371, 1792 (identical ?)
- Sittiquo – Doc. of 1755 quoted by Royce in 5th Rep. B.A.E., 142, 1887.
- Skeinah
- Soquee
- Spike Bucktown
- Spring Place
- Standing Peach Tree
- Stikayi
- Sutali
- Suwanee
- Tagwahi
- Tahlasi
- Takwashnaw
- Talahi
- Talaniyi
- Talking Rock
- Tallulah
- Tamahli
- Tanasqui (?)
- Tasetsi
- Taskigi
- Tausitu
- Tawsee
- Tekanitli
- Tellico
- Tennessee
- Tessuntee
- Tikaleyasuni
- Tikwalitsi
- Tlanusiyi
- Tocax
- Tomassee
- Toquo
- Torsalla
- Toxaway
- Tricentee
- Tsilaluhi
- Tsiskwahi
- Tsistetsiyi
- Tsistuyi
- Tsiyahi
- Tsudinuntiyi
- Tucharechee
- Tuckaseegee
- Tugaloo
- Turkeytown
- Turniptown
- Turtletown
- Tusquittah
- Two Runs
- Ustanali
- Ustisti
- Valleytown
- Wahyahi
- Wasasa
- Watauga
- Willstown
- Yunsawi
