Okeechobee is the Anglicization of the Itsate Creek (Miccosukee) words Oka chopi, which mean “Water Big.” Its aboriginal inhabitants called the lake either Maya-imi, which apparently means “Maya Water or Mayakaa, which means Maya People in several northern South American tongues. The Spanish called it Laguna de Mayaco or on some maps Laguna de Espiritu Santo. However, that name more typically applied to the Apalachicola-Chattahoochee River. In 1821, when Florida was ceded to the United States, the earliest English language maps generally retained the Mayaco name, but some called it Macaco.
Lake Okeechobee Indians
The Lake Okeechobee region contained some of the most sophisticated indigenous cultures that ever existed north of Mexico. Its towns built large earthworks and ponds in the shape of the ceremonial scepters carried by leaders in the Southeastern Ceremonial Mound Culture, but they were built several centuries before the Southeastern Ceremonial Mound Culture appeared elsewhere. Its engineers constructed several hundred miles of canals and raised causeways to interconnect the towns. They even built locks to enable cargo canoes to bypass rapids. Yet despite all this cultural precociousness, so far there is no evidence that the people of South Florida ever practiced large scale agriculture. However, intensive cultivation of raised garden beds in a semi-tropical climate, also a practice of the Mayas, may have produced a far higher percentage of their diet than anthropologists currently presume.