Ephraim, son of George Cotton, was born April 9, 1648. He settled in Longmeadow, and about 1696 removed to Enfield, Massachusetts. He died May 14, 1713. He married (first) November 17, 1670, Mary Drake, who died October 19, 1681. He married (second) March 26, 1685, Esther, daughter of Samuel and Catharine Marshfield. She died January 20, 1714. Children of first wife, born in Springfield; Ephraim, February 8, 1672; Josiah, October 7, 1674; Job, May 14, 1677; Samuel, January 17, 1679; children of second wife, the first five recorded in Springfield, the remainder in Enfield : Josiah, December 30, 1685; Esther, October 23, 1687; Benjamin, graduated at Yale College, 1710, settled in West Hartford; Sarah, March 12, 1692; Daniel, July 27, 1694; Deborah, April 22, 1697; Isaac, July 30, 1698; Margaret, May 9, 1701; Nathaniel, August 22, 1703; Thomas, August 3, 1705, killed by Indians, June 27, 1724; Noah, December 19, 1707; Mary, August 11, 1710; Abiel, January 13, 1714, died May 9, 1714.